Forms of drugs for infertility.
Medications are a normal and common part of infertility treatments and the in vitro fertilization (IVF) technique. These medications are used to prepare the body for treatment and increase the chance that the ovaries will release healthier eggs.
A reproductive professional can review your scenario to determine the most appropriate medications for your situation.
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The following medications are used for ovarian stimulation:
Clomiphene Citrate (CC): There are two varieties of medication, Clomid® and Serophene®. These medications work with the help of increasing the amount of FSH that is secreted by the pituitary gland. These are often used to stimulate ovulation in women who have missed periods, sporadic periods, or prolonged cycles.
Dosing normally starts at 50mg in the evening, for a set number of days. Dosing can be accelerated if ovulation has not yet occurred, although the chances of side results increase as the dosage increases. The American Society for Reproductive Medicine (ASRM) recommends that clomiphene be prescribed for a minimum of three to six cycles.
The results on the capacity side consist of:
- Accelerated occurrence of a pair of births
- Multiplied prevalence of miscarriage
- Hot flashes, nausea, and breast tenderness
- Headaches or blurred vision
- depression and mood swings
- Ovarian cysts and pelvic pain due to overstimulation of the ovaries
Artificial human chorionic gonadotropin (hCG): Intramuscular injections used to cause ovulation. It is often used when taking other medications to induce ovulation. Common human chorionic gonadotropin (hCG) medications include Pregnyl®, Profasi® Novarel®, and Ovidrel®. There are no recognized side effects if only hCG is taken.
Follicle-stimulating hormone (FSH): An injection given just under the skin (subcutaneous injection) that bypasses the hypothalamus and pituitary glands to immediately stimulate the growth of follicles in the ovaries. “Infertility drugs”
Common FSH medications include:
The consequences of the capacity aspect consist of:
- Improved incidence of a pair of births
- Improving the incidence of spontaneous abortions and preterm births
- Tenderness, swelling or rash in the breasts on the injection web page
- Mood swings and depression
- Hyperstimulation syndrome including enlarged ovaries, stomach pain, and bloating
Human menopausal gonadotropins (hMG): An injection that incorporates equal parts of FSH and LH (luteinizing hormone), given to stimulate the ovaries to deliver multiple eggs during a cycle. “Infertility drugs”
Common hMG medications include:
These are the most powerful ovulation drugs currently in use today. The capacity-side consequences are similar to those noted above for FSH.
Bromocriptine and cabergoline: Oral medications used to decrease the amount of prolactin released through the pituitary gland. The logo name for bromocriptine is Parlodel® and the logo name for cabergoline is Dostinex®. Consequences of the skill aspect include:
- Nausea, vomiting, nasal congestion
- Headache, dizziness, fainting
- Decrease in blood pressure
Gonadotropin Releasing Hormone (GnRH): An injection used to stimulate the pituitary gland to secrete LH and FSH. Common names for GnRH medications include Factrel® and Lutrepulse®. The results of the capacity facet include:
- Moderate probability of more than one birth
- Mild hyperstimulation including enlarged ovaries, abdominal pain, and bloating
- Complications and nausea
The following medications are used to prevent premature ovulation:
GnRH agonists (analogs): There are two varieties of medications. Lupron® and Zoladex® are injections given under the skin, and Synarel® is a nasal spray. Those medications are used to allow the body to produce a larger number of fine eggs. These medications are also designed to spare you from the mid-cycle hormonal surge that could cause cycle cancellation.
The effects of skill aspects include:
- warm flashes
- Humor changes
- vaginal dryness
- reduced breast size
- painful intercourse
- Bone density loss
GnRH antagonists: These medications, Ganirelix Acetate® and Cetrotide®, are injections given over 3 to 4 days. These medications work as antagonists to gonadotropin releasing hormone (GnRH) to help prevent premature ovulation. The results of the capacity aspect are similar to those of GnRH.
Other medications used for fertility enhancement remedies:
Medrol: A steroid given daily for 4 days at some stage of the cycle to help with pre-embryonic implantation.
doxycycline: An oral antibiotic given to the male partner during the female’s stimulation cycle to reduce the levels of bacteria found in semen. This drug is also given to the partner woman to reduce the risk of infection after aspiration of the follicles at the time of egg retrieval.
Progesterone: Intramuscular injections given daily beginning two days after delivery and ending while the placenta is creating adequate amounts of progesterone. Progesterone can be given through a vaginal gel, suppository, or tablet.
Dietary supplements for fertility: Many couples turn to natural, over-the-counter fertility supplements that contain vitamins, minerals, antioxidants, and/or herbs to help improve their reproductive health.